Washington: In a recent study, it has been found that chronic overeating and stress are tied to an increased risk of depression and anxiety.


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The researchers from Yale University report that the anesthetic ketamine reverses depression-like symptoms in rats which are fed a high-fat diet in a similar way it combats depression and synaptic damage of chronic stress in people.


Senior author Ronald Duman said that the effects of a high-fat diet overlap with those of chronic stress and could also be a contributing factor in depression as well as metabolic disorders such as Type 2 diabetes.


In the research scientists have shown that ketamine, also known as Special K and abused as a recreational drug, can quickly and dramatically reduce symptoms of chronic depression in patients, who are resistant to typical antidepressant agents.


They also found that a single low dose of ketamine reversed those symptoms quickly, and reversed the disruption of mTORC signaling pathways.


The research is published in the Journal, 'Neuropharmacology.'