The findings of the research were published in the journal ‘Environmental Health Perspectives’. In the UW-led study, a small increase in the levels of fine particle pollution (PM2.5 or particulate matter 2.5 micrometres or smaller) averaged over a decade at specific addresses in the Seattle area was associated with a greater risk of dementia for people living at those addresses.
First, plaques of amyloid proteins form, then tangles of tau protein. Some brain areas begin to shrink, and communication networks between distant parts of the brain start to decay Stark and colleagues have shown that the link between Alzheimer`s and falling holds true even during the silent phase of the disease People with so-called preclinical Alzheimer`s are at increased risk of falling despite having no apparent cognitive problems
Their findings show that the study participants who started out experiencing more fragmented sleep and less non-rapid eye movement slow-wave sleep were most likely to show an increase in beta-amyloid growth Although all participants remained healthy throughout the study period, the trajectory of their beta-amyloid growth correlated with baseline sleep quality The researchers were able to forecast the increase in beta-amyloid plaques, which are thought to mark the beginning of Alzheimer`s
An estimated 5 million Americans are living with Alzheimer`s, a progressive disease that affects mostly those over 65 and interferes with memory, language, and decision making Currently, there are no effective treatments or prevention strategies for Alzheimer`s. Experts have long linked it to a buildup of extra phosphate molecules on tau proteins The new study, publishing online in the journal Brain, provides what Drummond and her colleagues say is the largest overview to date of proteins present in these tau tangles
The study named `Behavioural issues in late life may be the precursor of dementia - A cross-sectional evidence from memory clinic of AIIMS, India` conducted by the Department of Geriatric medicine also stressed on multimorbidity, diabetes and urinary incontinence to be significantly associated with MBI.
For the analysis, the research team focused on the relationships between social contact at age 50, 60 and 70, and subsequent incidence of dementia, and whether social contact was linked to cognitive decline, after accounting for other factors such as education, employment, marital status and socioeconomic status.