ICMR warns 'Cat Que Virus' from China that could spread disease in India

New Delhi: ICMR scientists have flagged the presence of another Chinese virus called `Cat Que Virus`, which has a "potential" to cause disease in India, even as it grapples with the Covidpandemic. CQV can cause febrile illnesses, meningitis and paediatric encephalitis in humans.

According to the seven researchers at the Indian Council of Medical Research`s National Institute of Virology in Pune, the presence of Cat Que Virus in Culex mosquitoes and pigs has been reported in China and Vietnam. 

They added that due to the spread of similar species of the Culex mosquitoes in India, there is a need to understand the replication kinetics of this virus. The researchers said that the presence in Culex mosquitoes in China and pigs in Vietnam suggested the susceptibility of Asian countries to CQV.

The scientists discovered antibodies for the tropical virus in two out of the 883 human serum samples tested across states. It indicates that these two people were infected with the virus at some point of time. It was not found in any of the humans at the time of the study.

"Anti-CQV IgG antibody positivity in human serum samples tested and the replication capability of CQV in mosquitoes indicated a possible disease-causing potential of CQV in the Indian scenario. Screening of more human and swine serum samples using these assays is required as a proactive measure for understanding the prevalence of this neglected tropical virus,” research published in the Indian Journal of Medical Research in June stated.

In the Indian context, "data showed that mosquitoes such as Ae. aegypti, Cx. quinquefasciatus and Cx. Tritaeniorhynchus were susceptible to CQV. Thus, mosquitoes were found to be a potential vector for CQV transmission to mammalian hosts", a scientist stated.

According to the apex research body, domestic pigs are the primary mammalian host of CQV and antibodies against the virus have been reported in swine reared locally in China, indicating that CQV has formed a natural cycle in local areas.