US media reported that the woman's granddaughter, Lori Logli, confirmed the death but would not provide information about how she died.
Guinness World Records said Manfredini became the world's oldest living person earlier this month after Bessie Cooper of Georgia died at the age of 116.
Manfredini was born in Italy April 4, 1897 and left for Iowa in 1920 with her late husband, Ricardo, according to the NBC News.
"I m old, old lady, but I work," she told the Des Moines Register in 2004. "Work hard. I like work."
Washington: Less than two weeks after inheriting the title of the world's oldest living human being, 115-year-old Dina Manfredini, who was living in an Iowa nursing home died Monday, according to her family.
First Published: Tuesday, December 18, 2012, 09:21