Why Neanderthals never had brain disorders
Washington: In a significant discovery, scientists have found why modern humans develop brain disorders like autism or schizophrenia but our ancestor Neanderthals did not.
They have discovered the cellular equivalent of "on/off" switches that determine whether DNA is activated or not.
Hundreds of Neanderthals` genes were turned "off" while the identical genes in today`s humans are turned "on".
Alternatively, hundreds of other genes were turned "on" in Neanderthals but are "off" in people living today.
“The genes related to autism, as well as to schizophrenia and Alzheimer`s disease, were more likely to be "off" in Neanderthals than in modern humans,” said lead author Liram Carmel from Hebrew University of Jerusalem.
The discovery underlines the power of the "on/off" patterns.
“The `on/off` switches could also explain the anatomical differences between archaic and present-day humans, including Neanderthals` shorter legs and arms, bow-leggedness, large hands and fingers, and curved arm bones,” Carmel explained.
When dozens of brain-related genes became more active in today`s humans, that produced the harmful side effect of neurological illnesses, the study noted.
One person`s genome can vary markedly from another`s due to diet, environment and other factors.
“It is, therefore, impossible to know whether the `on/off` patterns found in Neanderthal genes are typical of the species overall or peculiar to the individual studied, the study, published in the journal Science, concluded.
More from India
More from World
More from Sports
More from Entertaiment
- Rajasthan: Gujjars revive reservation agitation, block rail track
- Dr Subhash Chandra Show: Aspiring for more than what you have!
- J Jayalalithaa sworn-in as Chief Minister of Tamil Nadu
- ISIS to buy first nuclear weapon from Pak?
- Mumbai: CCTV captures assailant with gun at Film City
- Mathura SSP receives death threat letter, message for PM Modi
- BJP now central pole of Indian politics: Arun Jaitley
- Maharashtra FDA sends Maggi noodles for lab testing
- Watch: Fast N Facts @ 7:30pm
- Reservation issue: Police register case against Bainsla, 20 others
- Haridwar: Hotel Radisson Blu sealed for polluting Ganga
- Zee Media exclusive chat with 'Welcome to Karachi' cast
- Zee Media exclusive interview with Haryana CM Manohar Lal Khattar
- Girl in Punjab's Pathankot quit studies for fear of eve-teasing
- Special: Furious over rising water crisis, people take to the streets
- Goa Board SSC Exam Results 2015 announced
- ISIS close to buying nuclear weapon from Pakistan?
- Credibility of Prime Minister's Office restored by BJP, says Arun Jaitley
- ISIS justifies raping slave girls, says Michelle Obama is 'worth $40'
- IPL 2015 Final: Mumbai Indians vs Chennai Super Kings - Preview
- Arvind Kejriwal to highlight AAP govt's 100 days work on Monday
- CBSE Results 2015: 10th board exam results to be declared on May 27
- BJP's plan for one-year celebration: 200 big rallies, 5,000 public meetings
- IPL 8 Final: We need to be at our best against Mumbai, says Michael Hussey
- Heatwave leaves 153 dead in Telangana, Andhra Pradesh
- IPL 2015 Final: MI vs CSK - As it happened...
- Heatwave kills 223 in AP, Telangana, Chandrababu Naidu announces compensation; Delhi records hottest day
- Heatwave continues in North India; death toll in Andhra Pradesh, Telangana more than 400
- 'Tanu Weds Manu Returns' starts on a good note at the Box Office!
- CBSE Results 2015: 12th board exam results to be declared on May 25