Washington: A new method has been developed by researchers that has the capability of looking at a specific segment of DNA and point out a single mutation, which could help diagnose and treat diseases like cancer and tuberculosis. These small changes can be the root of a disease or the reason some infectious diseases resist certain antibiotics. Lead author Georg Seelig, a University of Washington assistant professor of electrical engineering and of computer science and engineering said that the team has really improved on previous approaches because their solution doesn`t require any complicated reactions or added enzymes, it just uses DNA. He said that this means that the method is robust to changes in temperature and other environmental variables, making it well-suited for diagnostic applications in low-resource settings.Seelig, along with David Zhang of Rice University and Sherry Chen, a UW doctoral student in electrical engineering, designed probes that can pick out mutations in a single base pair in a target stretch of DNA.
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