New Delhi: A vaccine which produces arobust immune response at one go might make swine flu easierto handle, but authorities in India feel any such immunisationneeds intensive testing as it may compound any side effectsthe vaccine might have. According to Director of Indian Council of Health Research(ICMR), VM Katoch, any vaccine which is introduced in Indiawill have to be tested on the Indian population as any sideeffects which the vaccine might have will be compounded.
The findings suggest that one dose was enough to producean immunogenic response, with "mild to moderate" side effects. They also reported that the vaccine appears to have sideeffects similar to seasonal flu vaccines. Katoch said if a vaccine is administered in two or threedoses like in a normal flu vaccine, then if it has any sideeffects it would be clear after administering the first doseonly. But in a single shot vaccine which uses a adjoinder,nothing can be done to tackle side effects, he said. "We have written to all international companiesmanufacturing the vaccine and asked them to conduct bridgingstudies in India first. After that we would decide onprocuring them," he said. The CSL study is based on measures taken 21 days afterthe first of the two scheduled vaccine shots was given. "Over 95 per cent of participants receiving the single 15mcg dose of the vaccine achieved antibody levels thatcorrelate with the prevention of influenza infection," the CSLannounced in a statement.Bureau Report
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