Paternal eating habits have hereditary effect
Texas: Scientists have discovered evidence that environmental influences experienced by a father can be passed down to the next generation, "reprogramming" how genes function in offspring.
The new study, conducted by researchers at the University of Massachusetts Medical School and the University of Texas at Austin, shows that environmental cues—in this case, diet—influence genes in mammals from one generation to the next, evidence that until now has been sparse.
These insights, coupled with previous human epidemiological studies, suggest that paternal environmental effects may play a more important role in complex diseases such as diabetes and heart disease than previously believed.
"Knowing what your parents were doing before you were conceived is turning out to be important in determining what disease risk factors you may be carrying," said Oliver J. Rando, principal investigator for the study.
To test their hypothesis Rando and colleagues fed different diets to two groups of male mice.
The first group received a standard diet, while the second received a low-protein diet. To control for maternal influences, all females were fed the same, standard diet.
Rando and colleagues observed that offspring of the mice fed the low-protein diet exhibited a marked increase in the genes responsible for lipid and cholesterol synthesis in comparison to offspring of the control group fed the standard diet.
The study has been published this week in Cell.
More from India
More from World
More from Sports
More from Entertaiment
- Trump-Sharif conversation: Team Donald denies Pakistan's claims
- Hizbul commander Musa issues threats of attacks in new video
- 'Heart of Asia' Conference begins in Amritsar; Sartaj Aziz to pay a visit on Sunday
- Aware of Chinese submarine deployment at Balochistan's Gwadar port, says Navy chief
- Panel discussion over Mamata Banerjee's false allegations on Indian Army for political gains
- Gujarat businessman declares highest ever black money amount – Rs 13,000 crore!
- Army proves Mamata Banerjee wrong, releases letter showing West Bengal govt knew of exercise
- Rs 14,000 crore default case: Gujarat businessman detained, says money belongs to politicians, babus
- Manohar Parrikar exposes Mamata's attempt to politicise routine Army exercise in Kolkata
- Newly-wed couple Yuvraj Singh and Hazel Keech perform `bhangra` at Goa airport – Viral video