Scientists create 1st human heart cells paced with light

Last Updated: Tuesday, September 27, 2011 - 17:36

London: Researchers at the Stanford University in California have for the first time engineered human heart cells that can be paced with light.

In the study, the researchers inserted a gene found in algae into human embryonic stem cells, then made the cells differentiate into heart muscle cells.

The gene produces a light-sensitive protein called channelrhodopsin-2, which allows the cells to be switched on or off using pulses of light.

The technique could one day be used to activate pacemaker cells derived from a person’s own body.

“We would inject these engineered light-sensitive cells into the faulty heart, and pace them remotely with light,” New Scientist quoted co-author Christopher Zarins as saying.

ANI




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